genetics’ influence on drug abuse & addiction interactions of endophenotypes & genotypes

Genetics’ Influence on Drug Abuse & Addiction Interactions of Endophenotypes & Genotypes

A B S T R A C T “Addiction” is a multifaceted complicated disorder with many interrelated causes, as well as environmental and genetic features. Several hereditary variables that have an effect on these features might work in together to influence vulnerability and the extent of being an addict. Molecular re-sequencing of the latest and formerly researched genes holds a crucial place with regar...

Genetics’ Influence on Drug Abuse Interactions of Endophenotypes & Genotypes

" Addiction " is a multifaceted complicated disorder with many interrelated causes, as well as environmental and genetic features. Several hereditary variables that have an effect on these features might work in together to influence vulnerability and the extent of being an addict. Molecular re-sequencing of the latest and formerly researched genes holds a crucial place with regards to the brea...

Adolescents--drug abuse and addiction.

Drug taking by young people has been described and debated almost to saturation point by professional and lay people alike. This is not only because of the many connecting professional links in medicine, the law, the social sciences, moral philosophy, psychology, and education, but also because it has a personal impact on every young family in the country. No parent who has the welfare of his c...

Drug Abuse , Addiction and Dependence

Behavioral endophenotypes of drug addiction: Etiological insights from neuroimaging studies.

This article reviews recent advances in the elucidation of neurobehavioral endophenotypes associated with drug addiction made possible by the translational neuroimaging techniques magnetic resonance imaging (MRI) and positron emission tomography (PET). Increasingly, these non-invasive imaging approaches have been the catalyst for advancing our understanding of the etiology of drug addiction as ...

Drug Addiction Endophenotypes: Impulsive Versus Sensation-Seeking Personality Traits

BACKGROUND Genetic factors have been implicated in the development of substance abuse disorders, but the role of pre-existing vulnerability in addiction is still poorly understood. Personality traits of impulsivity and sensation-seeking are highly prevalent in chronic drug users and have been linked with an increased risk for substance abuse. However, it has not been clear whether these persona...